Nisreen Maghraby , Adnan F. Alfaraj
Opioid analgesics are commonly used in the hospitals. Tramadol is a synthetic opioid that is considered safe, and hypersensitivity reactions to this drug are rare. In this study, we report the first intramuscular tramadol-induced anaphylaxis case induced in an adult patient. This case indicates an important concept of detecting those reactions that include life threatening ones such as anaphylaxis in addition to the other commonly reported side effects. Keywords: Anaphylaxis, Hypersensitivity, Tramadol, Opioids, Analgesia.