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TITLE:

THE USE OF COMPUTED TOMOGRAPHY IN THE DIAGNOSIS OF FATTY LIVER AND LIVER CIRRHOSIS

AUTHORS:

Mohamed Albatania, Thamer Wadi Alanazi

ABSTRACT:

Background: Fat accumulation is one of the commonest liver abnormalities among patients undergoing cross-sectional imaging of the abdomen. CT scans is a preferred non-invasive method of diagnosing the presence and severity of fatty liver and liver cirrhosis. Objectives: to review the prevalence of diffuse fatty liver and liver cirrhosis disease and if there a relationship between diffuse fatty liver and liver cirrhosis disease and hepatomegaly, among patients under routine CT scan in KSA. Methods: Medline and PubMed database searches was performed for articles about the role of computed tomography in the diagnosis of fatty liver and liver cirrhosis and prevalence of diffuse fatty liver and liver cirrhosis disease and if there a relationship between diffuse fatty liver and liver cirrhosis disease and hepatomegaly, published in English around the world. The keyword search headings included “normal, liver cirrhosis, fatty liver, diagnosis, radiology and tomography ", and a combination of these will be used. References list of each included study will be searched for further supportive data. Results: Plain computed tomography is an accurate and reliable method that can be used easily to assess hepatic size and density . Current imaging methods such as ultrasound, CT, and MRI have demonstrated their values to serve as noninvasive imaging biomarkers to evaluate NAFLD progression, but they are still relatively limited in the detection of inflammation (NASH), which is more important than steatosis in terms of its high risk for fibrosis, cirrhosis, and HCC. Detection of NASH by imaging remains the future direction in NAFLD. Conclusion: Imaging studies like computed tomography (CT), magnetic resonance imaging and ultrasonography, computed tomography (CT), magnetic resonance imaging (MRI), and magnetic resonance spectroscopy (MRS), with these methods mostly used to quantify hepatic steatosis but the ultimate diagnosis requires liver biopsy Key words: Normal, liver cirrhosis, fatty liver, diagnosis, radiology.

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