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IMPACT OF PSYCHOLOGICAL INTERVENTION ON IMMUNITY FUNCTIONS AMONG PATIENTS WHO UNDERWENT LUNG CANCER SURGERY

Dr. Maryam Mazhar, Dr Maria Mustafa

Objective: The purpose of this study is to examine the impact of psychological intervention on immunity system, pain and adrenocortical functions in the patients getting the lung cancer surgery. Methodology: We recruited one hundred and twenty-four patients who underwent surgery for the treatment of Stage-1 or Stage-2 lungs cancer and we separated the patients into control and experimental groups. We gave the comprehensive psychological intervention to the patients of experimental group whereas the patients of control group obtained the conventional intervention. We evaluated the pain in the patients of two groups with the use of VAS (Visual Analog Scale). Prior and post intervention, we measured the levels of free cortisol, CD3+, CD4+, CD8+ and CD4+ / CD8+ in serum. We also used the QLQ-C30 which is a scale for the measurement of life quality by the EORTC (European Organization for Research and Treatment of Cancer). Results: In comparison with the patients of control group, pain scores of experimental group reduced before application of anesthesia, six hours, twelve hours, twenty-four hour and two days after surgical intervention (P < 0.05), and moreover the scores of QLQ-C30 in the patients of experimental group were very high (P < 0.05). We found no significant disparity immune index among the patients of both groups prior surgery (P > 0.05). The disparities of CD3+, CD4+ and level of free cortisol prior and post-surgical intervention were significant in both groups (P < 0.05). Conclusion: Broad psychological intervention can effectually give relieve from pain, provide improvement in the immunity functions and increases the QoL (Quality of Life) for the patients who were facing surgery for lung cancer. KEY WORDS: Surgical Intervention, Immunity, Anesthesia, Psychological, Lung Cancer, Significant Disparity.