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HCV INFECTION AND TYPE II DM: A CROSS SECTIONAL STUDY

1Dr. SYED MOHSIN ALI, 2 Dr. SYEDA UMM A OMARAH GILANI, 3Dr. SYEDA AMINA BATOOL

1School of Medicine and Nursing, Dezhou University, Shandong, China 2Lenox Hill Medical Diagnostic Imaging Center, New York 3Kishwar Fazal Teaching Hospital, Sheikhupura, Pakistan

Objective; To determine the frequency of type II DM in cases of chronic HCV infection. Material and methods; This was a cross sectional study conducted at Kishwar Fazal Teaching Hospital, Sheikhupura, Pakistan during July to December 2018. In the present study, 200 cases with age range of 18 to 60 years of either gender having known history of HCV infection and no previous history of DM were included. HCV was detected on PCR by qualitative method. DM was labeled as yes where the fasting blood glucose was more than 126 mg/dl. Results; A total of 200 patients of chronic hepatitis C were included in the study. Out of 200 patients, 120 were males (60%) and 80 (40%) were females. The mean age of patients was 47.25 ± 11.02 (SD) with the range of 35-74 years. The frequency of diabetes mellitus among hepatitis C patients was seen in 56 (28%). Out of 56 diabetic patients, 30 (53.57%) had positive family history of Diabetes Mellitus (p = 0.001). Of the 56 diabetics, only 14 had BMI less than 25 kg/m2 while 42 had BMI more than 25 (p =0.009). Conclusion; Type 2 Diabetes Mellitus occur frequently in patients with chronic Hepatitis C infection. Positive family history of diabetes mellitus and increased BMI are significantly associated with this. Key word; HCV infection, type II DM