ResearcherID - CLICK HERE Scientific Journal Impact Factor (SJIF-2020) - CLICK HERE

TITLE:

COMPARISON OF KETAMINE AND LIGNOCAINE INFUSION FOR ATTENUATION OF TOURNIQUET INDUCED HYPERTENSION IN UPPER AND LOWER LIMB ORTHOPEDIC SURGERIES

AUTHORS:

Dr. Tooba Nawaz, Prof. Dr. Muhammad Ashraf Zia, Dr. Shahzad Imran, Dr. Faiza Afzaal, Dr. Aqeel Ahmad

ABSTRACT:

Objective: To compare frequency of tourniquet induced hypertension in patients undergoing limb surgery after administration of lignocaine infusion vs Ketamine. Material and methods: This randomized controlled trial was conducted at Department of Anesthesia, Pak red crescent medical and dental college, Dina Nath, Kasur from September 2017 to October 2018. Total 300 patients undergoing orthopedic surgery of limbs involving tourniquet time >45 minutes, with ASA status I & II, both male and female having age 18-50 years were selected. Patients were randomized (by lottery method) into two groups: group A (lignocaine) and group B (Ketamine). Tourniquet induced hypertension was assessed between the both groups. Results: A total of 300 patients (150 in each group) were included in the study. The mean age of the patients was found to be 38.14 ± 8.67 years in group A and 38.59 ± 8.93 years in group B. Gender distribution of the patients showed that in both groups most of the patients were male. Similarly most of the patients in this study had upper limb involved in group A while lower limb involved in group B. The main outcome of this study was to determine frequency of TIH in both groups. It was found in 46 patients in group A while in 24 patients in group B (p= 0.003). TIH was stratified according to age, gender, BMI and limb involved and results were found significant for higher age, female gender, high BMI and lower limb involved. Conclusion: We conclude that Ketamine is better than Lignocaine infusion as it had ess frequency of tourniquet induced hypertension in patients undergoing limb surgery. Therefore I recommend usage of Ketmaine to reduce the morbidity of the patients. KEYWORDS: Ketamine; Lignocaine; Tourniquet; Hypertension

Top
  • Follows us on
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.