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RISK OF COMPLICATIONS OF PREGNANCY IN WOMEN WITH TYPE 1 DIABETES: A NATIONWIDE PROSPECTIVE STUDY

Dr. Asma Mushtaq, Dr. Muhammad Tanveer Ashraf, Dr. iqra Shah Jahan

This study is based on nationwide cohort prospective for the investigation of neonatal, maternal and perinatal results of pregnancies in female patients specifically with “type 1 diabetes” according to data taken by PubMed Database for the 118 hospitals in the Netherlands. There were 323 women who become pregnant with type 1 diabetes between (as per data record of PubMed Database) 1st April 1999 and 1st April 2000. There were perinatal, neonatal and maternal outcomes of pregnancy. Pregnancies were planned (n=271) 84% and in pregnancy, the glycaemic control at initial was better with many women “HbA1c 7.0% (n=212) in 75% of the population as prescribed in PubMed Database), accordingly there were also reports for folic acid supplements that it was adequate (n=226) in 70%. Pre-eclampsia rates (40;12.7%) caesarean section (139; 44.3%), delivery of preterm (101;32.2%), maternal mortality (2;0.6%), perinatal mortality (9;2.8%), congenital malformations (29; 8.8%) and there was macrosomia (146; 45.1%) which is significantly greater as compared with general population. With one or more than one complication “neonatal morbidity” was very high (with the ratio of 260; 80.2%). The main congenital malformation incidence was importantly lower in these deliberated pregnancies than in unintended pregnancies as (4.2% (n=11) v 12.2 (n=6) with 95% confidence interval 0.13 to 0.88 and with relative risk 0.34. Besides high frequencies of intended pregnancies, in diabetes type 1 woman; there are results which showed good glycaemic initially control, folic acid high adequate rate and increased perinatal and maternal complications.

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