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TITLE:

HEMATOLOGICAL PARAMETERS IN DENGUE POSITVE PATIENTS AT NORTHWEST GENERAL HOSPITAL AND RESEARCH CENTER PESHAWAR PAKISTAN

AUTHORS:

Dr. Naeem Ullah, Dr Rimsha Irfan, Dr.Farwa Inayat

ABSTRACT:

Dengue virus, a mosquito-borne human viral pathogen, which cause dengue fever and sometime cause severe condition like dengue hemorrhagic fever, dengue shock syndrome and has recently become a major health problem especially in equatorial and sub equatorial region. Importance of study was to interpret hematological parameters with sero-positivity of dengue thus management of dengue will be easy. This is a cross- sectional study carried out in the department of general medicine at Northwest General Hospital and Research center Peshawar Pakistan. This study includes 111 patients admitted in hospital and identified positive for dengue virus.Out of 111 cases 74 (66.66 %) were male and 37(33.33%) were female, majority of cases belongs to age groups 21 – 30 years. Thrombocytopenia was found in 50(44.35%) cases, raised hematocrit value >45 in 28(25.22%) cases, leucopenia (<4000) in 16(14.41%) cases and hemoglobin >18 in 2(1.80%) cases. Male and young adult are more commonly affected by dengue. Most of the cases were NS1 antigen positive. The most common laboratory abnormality is low platelet count (thrombocytopenia), low leukocyte count (leucopenia), raised hemoglobin and raised hematocrit. Key words: Dengue, hematological parameters, thrombocytopenia, leucopenia, HCT

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