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TITLE:

THE EFFICIENCY OF TIOTROPIUM IN THE CHILDREN SUFFERING WITH THE DISEASE OF ASTHMA

AUTHORS:

Dr. Shah Faisal, Dr. Khizra Amjad, Dr. Pir Mubassir shah

ABSTRACT:

Objective: The purpose of this research work is to enquire the medical effectiveness of tiotropium in children suffering with the disease of asthma. Methodology: About 80 children with recently detected medium level asthma were the participants of this research work. The separation of the children carried out into the group of fluticasone propionate aerosol or the group of fluticasone propionate aerosol + tiotropium for consecutive twelve weeks. Results: The function of the lungs was considerably better in all groups at four, eight and twelve weeks in accordance with the baseline. In addition, the function of the lung was better in the group of tiotropium as compared to the group of the controls. There was no important disparity in the occurrence of the serious nature asthma among the participants of both groups with 36.3% & 26.8% respectively. The amount of the days and the rates of the short-acting beta-two adrenoceptor agonist utilization were much lower in the group of tiotropium as compared to the group of controls. There were no serious side effects in the participants of both groups. Conclusion: Tiotropium has the ability to improve the function of the lungs, decrease the utilization of the short acting beta two adrenoceptor agonists & increase the sleeping period in the patients of asthma especially children. There is an availability of some minor side effects. Key Words: Asthma, Baseline, Hyper Sensitivity, Lenience, Tiotropium, cholinergic Receptor, Fluticasone.

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