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A COMPREHENSIVE STUDY ON THE ROLE OF PARATHYROID HORMONE AND VITAMIN-D IN HYPERTENSION AND BLOOD PRESSURE

Dr. Maryam Ahmad, Dr. Ayesha Shahjahan, Dr. Jannat Gulzar

Introduction: Hypertension is one of the important risk factors for cardiovascular disease, which is the major cause of morbidity and mortality worldwide. Vitamin D is known to regulate calcium and phosphate metabolism. Aims and objectives: The basic aim of the study is to find the role of Parathyroid hormone and Vitamin-D in Hypertension and blood pressure. Material and methods: This study was conducted at DHQ hospital Mandi Bahauddin with the collaboration of SIMS, Lahore during 2018. This study was conducted on 100 patients which was suffering from hypertension and visit the hospital regularly. The participants with hypertension were divided based on the stage of hypertension according to the definition of Joint of National Committee for hypertension. Results: Calcium, Vitamin D and PTH levels significantly decreased in all hypertensive patients with a cure rate of 99.1%. The mean systolic and diastolic BP decreased in the total population of hypertensive patients and hypertensive patients on antihypertensive therapy. Patients with PHPT experienced a significant decrease in both systolic BP (P < .001) and diastolic BP. High BP was present in 34% of the whole sample, and another 16% were taking medication for hypertension. Conclusion: It is concluded that serum vitamin D and PTH levels are not independently associated with blood pressure or risk of hypertension

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