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A REVIEW ON CURRENT TRENDS OF NANOEMULSION

Shaikh Neha M. , Vijayendra Swamy S. M. , Nagoba Shivappa N.*, Shaikh Atiya L.

The Nanoemulsions have the potential in pharmaceutical industries because of the transparency at high droplet volume fraction, higher rate of bioavailability or diffusion and increased shelf life of the pharmaceuticals. Nanoemulsions are submicron sized emulsions that are under investigation as drug carriers for improving the delivery of therapeutic agents. These are clear, thermodynamically stable, isotropic liquid mixtures of oil, water, surfactant and co-surfactant. Reduction in droplet size to nanoscale leads to change in physical properties such as optical transparency and unusual elastic behaviour. Nanoemulsion droplet sizes are ranges from 20- 200nm and shows narrow size distribution. It is focused to give the brief regarding formulation aspect, evaluation parameters and various application of the nanoemulsions, several techniques are to be used for preparation of nanoemulsions like microfluidization, high pressure homogenization, low energy emulsification and solvent evaporation method and parameter that are to be used for its characterization like droplet size analysis, viscosity determination, drug content, refractive index, pH, zeta potential, SEM, Transmission electron microscopy, thermal stability, drug release and in vitro skin permeation study. Nanoemulsions have widespread applications in different fields such as pharmaceutics, targeted drug delivery, food technology etc. Key words: Nanoemulsion, Surfactant, Co-surfactant, High pressure homogenization, Emulsification.

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