ResearcherID - CLICK HERE Scientific Journal Impact Factor (SJIF-2020) - CLICK HERE

PHYTOCHEMICAL INVESTIGATION AND BIOLOGICAL ACTIVITIES OF FIVE MEDICINAL PLANTS OF BALOCHISTAN

Saima Maher*, Zarbakht Dar, Suad Naheed, Shazia Iqbal, Noureen Khan, Farida Behlil, Nadra Naheed,Najma Sabzal, Mah Gunj Bakhshi

The studies show the medicinal plants with emphasis on their antimicrobial, antioxidant properties of Foeniculum vulgare, Cuminum cyminum, Pegnum harmala, Rosmarinus officinalis and Chenopodium album. Agar-well diffusion method was used for antimicrobial and antioxidant activity which was performed by DPPH (2,2-diphenyl1picrylhydrazyl) assay. The extracts of C. cyminum, C. album and P. harmala showed promising inhibitory effects against Pseudomonas aeruginosa with zones of inhibitions 27 mm, 22 mm and 17 mm respectively. C. cyminum and P. harmala exhibited highest antibacterial potential against Klebsella pneumonia. Whereas, among the crude methanolic extracts of the tested plants only F. vulgare, and P. harmala were also used for antifungal analyzation. Both plants showed the potential effects against the selected fungus (Aspergillus Niger) with inhibition zones of 18 mm and 13 mm respectively. On the other hand, all the selected plant showed significance antioxidant potential up to 98 % RSA. The study showed that a selected medicinal plant possesses potential against microbes and therapeutic significance. Keywords: Foeniculum vulgare, Cuminum cyminum, Pegnum harmala, Antibacterial activity, Antioxidant activity

FULL TEXT