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TITLE:

A REVIEW ON NIOSOMES AS TARGETED DRUG DELIVERY SYSTEM

AUTHORS:

Shaikh Atiya L.1 , Nagoba Shivappa N.1*, Wadulkar R. D. 1 , Shaikh Neha M. 1 , Pattewar S. G.1

ABSTRACT:

The advanced technique is a targeted drug delivery in which drugs deliver to the patients in a targeted sequences that increases the absorption of delivered drug to the targeted body part only (organs, tissues, cells) which in turn improves efficacy of treatment by reducing side effects of drug administration. Principally targeted drug delivery is to help the drug molecule to reach first to the desired site. The inherent benefit of this technique leads to administration of necessary drug with its reduced dose and reduced its side effect. This important benefit of targeted drug delivery system is under high consideration of research and development in clinical and pharmaceutical fields as backbone of therapeutics & diagnostics as well. Various drug carriers which can be used in this advanced delivery system are soluble polymers, biodegradable microsphere polymers (synthetic and natural), niosomes, liposomes, micelles and immune micelle etc. The purpose of a targeted drug delivery system is to target, localize, prolong and have a protected drug interaction with the diseased tissue. This review exhibits the significance of vesicular drug delivery (niosomes, liposomes) as one of the future targeted delivery system. Furthermore it depicts the advantages, disadvantages, preparation methods and characterization of niosomes. Keywords: Targeted drug delivery, Niosomes, Method of preparation of niosomes, Characterization of niosomes.

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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.