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AN OVERVIEW OF DIAGNOSIS AND MANAGEMENT OF INTERSTITIAL NEPHRITIS

Maad Saad Altalhi, Mamdouh Mohammed Mahbub, Abdullah Hamed Alsufyani,Yazeed Abdullah Alsufyani

Interstitial nephritis is a kidney condition characterized by swelling in between the kidney tubules. Acute interstitial nephritis (AIN) is frequently the result of a reaction. In this review we will discuss the diagnosis methods of IN and management methods of my most common type of AIN, drug-induced. We performed a narrative review using MEDLINE, EMBASE, CINAHL, from inception until August 2018 with predefined search terms. Studies that discussed the diagnosis and management approaches of interstitial nephritis were included. commonly associated with a hypersensitivity triad of high temperature, breakout, and eosinophilia. a definitive medical diagnosis is developed just by histopathological assessment. The mainstay of treatment for drug-induced AIN is discontinuation of the original medication. Although the benefits of steroid therapy remain unverified, steroids do appear to reduce the period of AKI in some patients and also might be connected with more total renal healing if used within 2 weeks of diagnosis. Steroids are typically advantageous unless advanced kidney failing is present or a contraindication exists. As the number of drugs utilized in clinical process boosts, doctors need to recognize the possibility of druginduced AIN as a relatively typical reason for AKI and various other scientific kidney syndromes.

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