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CAUSES AND MANAGEMENT OF OSTEOMYELITIS

Ammar Fareed Qutub , Alaa Jamal Akbar , Ghassan Abdulhamid Alnajjar , Mahdi Hussain Al-Saad , Abdulrahman Jubair M Aljubair , Shroug Ali Algoba , Ali Mohammed Ali Almousa

Introduction: Depending on the infection’s particular features (etiology, pathogenesis, extent of bone involvement, and duration) and the patient (infant, child, adult, or immunocompromised) a variety of challenges is present of osteomyelitis in long bones. Tremendous progress was made in the four past decades in the treatment of osteomyelitis as the many factors that account for the occurrence and persistence of infection have been found and a variety of antimicrobials with other spectrums of activity against microbes have been developed. Aim of work: In this review, we will discuss etiology, presentation, diagnosis, and management of osteomyelitis Methodology: We conducted this review using a comprehensive search of MEDLINE, PubMed, and EMBASE, January 1985, through February 2017. The following search terms were used: osteomyelitis, causes of osteomyelitis, diagnosis of osteomyelitis, treatment of osteomyelitis Conclusions: Treatment of long bone osteomyelitis is hard and is a significant cause of morbidity and expense. The aim of treatment is to stop the spread of osteomyelitis and repair the damage it has caused. Proper therapy consists of culture-directed antibiotic therapy and surgical debridement of all bone with necrosis and soft tissue. Antibiotic therapy (including a combination of antibiotics and a variety of delivery systems), debridement (often multiple), dead space management, soft tissue coverage, restoration of blood supply, and stabilization, are the stages of treatment Key words: osteomyelitis, bone infection, infectious diseases.

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CAUSES AND MANAGEMENT OF OSTEOMYELITIS

Ammar Fareed Qutub1 , Alaa Jamal Akbar1 , Ghassan Abdulhamid Alnajjar2 , Mahdi Hussain Al-Saad3 , Abdulrahman Jubair M Aljubair4 , Shroug Ali Algoba5 , Ali Mohammed Ali Almousa6

Introduction: Depending on the infection’s particular features (etiology, pathogenesis, extent of bone involvement, and duration) and the patient (infant, child, adult, or immunocompromised) a variety of challenges is present of osteomyelitis in long bones. Tremendous progress was made in the four past decades in the treatment of osteomyelitis as the many factors that account for the occurrence and persistence of infection have been found and a variety of antimicrobials with other spectrums of activity against microbes have been developed. Aim of work: In this review, we will discuss etiology, presentation, diagnosis, and management of osteomyelitis Methodology: We conducted this review using a comprehensive search of MEDLINE, PubMed, and EMBASE, January 1985, through February 2017. The following search terms were used: osteomyelitis, causes of osteomyelitis, diagnosis of osteomyelitis, treatment of osteomyelitis Conclusions: Treatment of long bone osteomyelitis is hard and is a significant cause of morbidity and expense. The aim of treatment is to stop the spread of osteomyelitis and repair the damage it has caused. Proper therapy consists of culture-directed antibiotic therapy and surgical debridement of all bone with necrosis and soft tissue. Antibiotic therapy (including a combination of antibiotics and a variety of delivery systems), debridement (often multiple), dead space management, soft tissue coverage, restoration of blood supply, and stabilization, are the stages of treatment Key words: osteomyelitis, bone infection, infectious diseases

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