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TITLE:

MANAGEMENT OF TOXIC MEGACOLON

AUTHORS:

Ahmed Anis Abdullah , Mohammed Jamal Goname , Sultan Ashraf Othman , Fahdah Khaled musallam , Asaad saleh radwan , Muayyad Abdullah Abualjadayel , SALIM AHMED ALAZMI , Hattan Saad Alshehri , Zainab Salman Al Shuhayb , Eman ahmed alabdrabalrasol

ABSTRACT:

Introduction: Toxic megacolon is differentiated from different types of colonic expansion, for example, Ogilvie syndrome and Hirschsprung disease by the extra presence of systemic toxicity and the incendiary or irresistible etiology of the hidden disease. Albeit toxic megacolon might be viewed as uncommon, frequency is expected to increase due to the quickly expanding prevalence of pseudomembranous colitis. Because early discovery and intervention profoundly affect survival, it is important that physicians know about this possibly lethal complication to attenuate morbidity and mortality Aim of work: In this review, we will discuss study of disease transmission, etiology, pathophysiology, clinical signs and symptoms, emergency management, and prognosis of toxic megacolon in adults. Methodology: We conducted this review using a comprehensive search of MEDLINE, PubMed, and EMBASE, January 1985, through February 2017. The following search terms were used: toxic megacolon, presentation and management of toxic megacolon, gastrointestinal pathology, ulcerative colitis, inflammatory bowel disease Conclusions: In summary, surgical intervention remains a pillar in the management of TM. Albeit short trials of therapeutic treatment are surely warranted, any indication of complication (either clinically or on CT scan), worsening, or inability to improve must be sign for colectomy. surgeons ought to be consulted early over the span of the disease, and frequent surgical reconsideration is critical. excessive delays will probably prompt pointless morbidity and mortality. Key words: Toxic Megacolon, Inflammatory Bowel Disease, Ulcerative Colitis.

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