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PREVEALING THE EFFECTIVENESS IN COMBINE USE OF VITAMIN B1, B6 AND B12 FOR TREATMENT OF DIABETIC PERIPHERAL NEUROPATHY

Dr. Sana Rana, Dr. Maria Rasool, Dr. Chandf Javaria

Abstract :

Objective: The purpose of our study was to find out the treatment effectiveness of the diabetic peripheral neuropathy with combine use of vitamin B1, B6 and B12. Study Design: Case control study on series of descriptive cases. Place and Duration: This study was carried out in the time period of 12 months starting from August, 2017 to September 2018 in Medical intensive care unit of Bahawal Victoria Hospital, Bahawalpur. Methodology: In this study the total numbers of patients selected were 310, who were having Endocrinology problem, Metabolism infection, diabetes mellitus and diabetic peripheral neuropathy. Unintentional sampling technique was used for selection of the samples. On the first visit, patients were described with Neurobion Tab (vitamin B1 & B6 100mg, B12 200cmg) for twice/day for the duration of one month and then they were called for followed checkup. According to the findings of our study the effectiveness was calculated with an enhancement in at least 2 pain points from the standard evaluated by the numerical pain rating scale. Results: Mean age of the patients was 46.70±8.60. Ratio of males and females out of total 310 patients was as 177 (57.0%) and 133 (42.90%) respectively. Periodic duration of diabetes as 0-10, 11-20, 21-30 and >30 years was found as 84 (27.09%), 138 (44.52%), 76 (24.52%) and 12 (3.87%) in all patients. Effectiveness rate of vitamin B1, B6 and B12 combination was 86.94% (270), during the treatment of diabetic peripheral neuropathy. Conclusion: According to the findings of our study treatment through combined vitamin B1, B6 and B12 were found effective in diabetic peripheral neuropathy. Key words: Vitamin B1, Vitamin B6 and vitamin B12, Diabetic peripheral neuropathy.

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