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TITLE:

A RESEARCH TO REVIEW THE DYSLIPIDEMIA PROTOTYPE IN THE PATIENTS OF TYPE II DIABETES MELLITUS (T2DM) WITH RESPECT TO INSULIN LEVEL AND AGE

AUTHORS:

Dr. Sana Suleman, Dr. Nida Afzal, Dr. Samia Rahman

ABSTRACT:

Objectives: The main purpose of the study is to revise the prototype of dyslipidaemia in Type 2 Diabetes Mellitus patients. To find out the relationship between the duration of disease of dyslipidaemia with the growing age and insulin level and insulin confrontation in patients is also an important objective of the study arranged. Methods: The study organized was of collaborative type. It was organized in Jinnah Hospital, Lahore from November 2016 to December 2017. The study consisted of patients of Type 2 Diabetes Mellitus and healthy persons as a control group. In both the patients and control groups serum level of Cholesterol, triglycerides, low weight lipoproteins, high-weight lipoprotein and insulin were observed. Homeostatic Model of Assessment of Insulin resistance was used by the investigators to check the opposition or resistance of insulin. Biochemical parameters were also used to identify the relationship between time extent of the illness and enhancement in age. The arithmetic investigation was completed by using SPSS. Results: Total 112 persons were included in the study. Out of these 72 were sufferers and 40 were normal or healthy individuals as a control group. It was found in the result of the study that hypertriglyceridemia was most commonly presentation in about 44 patients while the low weight-lipoprotein-hypercholesterolemia was the second most frequently occurring which was present in about 36 patients. While 20 sufferers of low-weight-lipoprotein hypercholesterolemia and 17 of hypertriglyceridemia were observed in control or healthy group. Dyslipidaemia or insulin opposition had no effect on length time of the disease. Serum insulin levels and length of disease greatly affect each other in a negative way. On regression investigation, it was concluded that age doesn’t affect the dyslipidaemia, serum insulin level or insulin confrontation. Conclusion: It was concluded from the study that hypertriglyceridaemia was the most frequently present dyslipidaemia. Hypercholesterolemia was a menacing aspect of vigorous persons. In addition to this, it was also resulted out that length o disease was inversely related with serum insulin levels and its association is positive with dyslipidaemia. Keywords: Diabetes mellitus, Dyslipidaemia, Insulin opposition.

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