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HISTOPATHOLOGICAL LESIONS OF UPPER GASTROINTESTINAL TRACT

Dr. Nand Lal Seerani, Dr. Gordhan Soothar, Dr. Tufail Ahmed Baloch, Hamid Nawaz Ali Memon, Dr. Samar Raza and Dr. Ali Raza Shaikh

OBJECTIVE: To determine the histopathological lesions of upper gastrointestinal tract PATIENTS AND METHODS:The present cross sectional study included endoscopic biopsies of upper GIT from patients at tertiary care hospital. The brief clinical data were recorded; the inclusion criteria were the patients of age ≥ 18 years either gender presented with abdominal pain and discomfort, dyspepsia, malena and haemetemesis were explored and included in the study while the frequency / percentages (%) and means ±SD computed for study variables. RESULTS:During six month study period total fifty patients had upper gi endoscopy and were explored thoroughly. the frequency for male and female population was 30 (60%) and 20 (40%) with mean ± SD for age of male and female individuals was 52.66±7.77 and 50.99±5.99 respectively. male 30 (60%) and female 20 (40%), regarding endoscopic biopsies esophagus 14 (28%), gastro-esophageal junction 11 (22%), stomach 13 (26%), duodenum 12 (24%) while regarding non-neoplastic lesions gastritis 07 14, granulomatous lesion 04 (8.0%) dysplasia 06 (12%), polyp 02 (4.0%) whereas regarding the neoplastic lesions squamous cell carcinoma 08 (16%), adenocarcinoma 10 (20%), adenosquamous carcinoma 07 (14%), non-hodgkin’s lymphoma 06 (12%). CONCLUSION:The non-neoplastic lesion comprises gastritis, granulomatous lesion, dysplasia and polyp while the most common neoplastic lesions were squamous cell carcinoma, adenocarcinoma, adenosquamous carcinoma and non-Hodgkin’s lymphoma. KEYWORDS:Gastritis, Malignancy and Gastrointestinal.

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