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LIPID ABNORMALITIES IN NON-DIABETIC, NON-OBESE AND HYPERTENSIVE PATIENTS

Dr Negarish Batool, Dr Yasir Bostaan, Dr Joham Javed

Objective: Dyslipidemia and hypertension are the main factors contributing to the coronary artery disease pathogenesis, and coexistence does not increase risk, but increases. The objective of this study was to govern the incidence of dyslipidemia in obese and non-diabetic patients with hypertension and to compare them with obese and non-diabetic patients with normotension. Methods: This case control study was conducted at Medicine Unit II of Jinnah Hospital Lahore for Six months duration from January 2019 to June 2019. The study included 120 adults of any sex; Forty, not obese, without diabetes, with hypertension and 80 without obesity, without diabetes, with normotension. Demographics and eating habits were recorded for each patient using a questionnaire. The blood glucose levels and fasting lipid profile were assessed in all patients. All data were compared among 2 groups. Results: In the hypertensive group low density lipoprotein cholesterol (LDL-C), triglyceride levels (TG) and total cholesterol (TC) were higher and lower value for high density lipoprotein cholesterol (HDL-C) than normotensive group. Only in men and TG, CT, LDL-C, HDL-C abnormalities were more common and in the group with hypertension TG was common (ratio = 2.96, 2.67, 4.28 and 4.57). HDL-C abnormality was similar in both groups (ratio = 1.47). Conclusion: People with hypertension are more prone to various lipid abnormalities, i.e. LDL-C, Total cholesterol and HDL-C (male) and triglycerides than the normotensive population. Keywords: not obese, without diabetes, hypertension and dyslipidemia.

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