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TITLE:

EVALUATION OF THE RELATIONSHIP BETWEEN PR AND GASTRIC MALIGNANT GROWTH AFTER THE DESTRUCTION OF H. PYLORI

AUTHORS:

Muhammad Hussain Khan Sajawal, Muhammad Rizwan, Muhammad Asad Jamal

ABSTRACT:

Aim: The characteristic endoscopic highlights of the gastric mucosa, which are signs of malignant growth after the successful annihilation of H. Pylori, have not been fully explained. We recently detailed an inversion of the red and white tint of the gastric corpus in some patients after destruction, and referred to it as the "wonder of inversion on the marginal mucous membrane" (RP), which is regularly visible in patients who create gastric malignant growth after annihilation. In this way, we conducted a cross-sectional study to evaluate the relationship between PR and gastric malignant growth after the destruction of H. Pylori, and we analyzed PR histologically. Materials and Methods: Our current research was conducted at Mayo Hospital, Lahore. Patients with a history of successful annihilation who underwent esophago-gastro-duodenoscopy in our clinic between March 2017 and May 2018 were temporarily enrolled. The quantities of tumour recently analyzed in positive and negative PR samples were evaluated. In addition, the red and white areas of RP-positive patients were examined by thin-band imaging with amplifying endoscopy, and histologically examined using examples of biopsies. Results: Eighty-five patients were examined. Of these, 30 (34.8%) indicated RP. Six malignant tumour were found in the RP-positive group and one in the RP-negative group (p<0.02). NBI-ME appeared as round pits without light blue peaks in white areas, and round pits with PLC-shaped structures or villus with PLC or dark white substance in red areas. All examples of white zone biopsies had background organs, and all those of red territories showed intestinal metaplasia. Conclusion: Patients with RA usually develop gastric disease after annihilation. Keywords: Gastric cancer, H. Pylori, Eradication therapy, Magnify┬Čing endoscopy, Narrow-band imaging.

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