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THE IMPACT OF SUCCINYLCHOLINE OR VECURONIUM ON INTRAOCULAR PRESSURE IN RELATION TO THE ACCEPTANCE OF PROPOFOL

Dr Talha Iqbal, Dr Muhammad Asjad Sohail, Dr Junaid Khan

Background and Aim: The performance of the ophthalmic medical procedure, especially once globe is open, be contingent to a large amount on the measure of the intraocular pressure during anaesthesia, nevertheless similarly during the support period. Intubation is typically accomplished through usage of non-depolarizing muscle relaxants inspired by a paranoid dread of swelling intraocular pressure through depolarizing relaxants. The current review has been embraced with a plan to assess impact of succinylcholine or vecuronium on intraocular pressure in relation to the acceptance of propofol. Methods: This existing research was conducted at Jinnah Hospital, Lahore from October 2017 to September 2018. Sixty cases of mutually genders with ASA status I and II, aged 16 to 52 years, remained designated for examination for one year. Cases through medically enormous ocular disease, elevated IOP, cardiorespiratory disease, CNS disease, difficult airway, corpulence, those receiving medications that may affect IOP, and in whom the usage of succinylcholine is contraindicated, were prohibited. Cases were arbitrarily divided into two equivalent sets. Anesthesia was encouraged through propofol 2 mg/kg for more than 36 seconds in all cases. In Set V cases, vecuronium was applied and in Set S cases, succinylcholine was used for intubation. The factual investigation was concluded with a unidirectional ANOVA using SPSS 23 programming rendering. Results: In Set V, the reduction in IOP of 29.48% after enrollment and one minute after intubation was increased to 15.54%, but remained below the gauge estimate. In Set S, there was a 29.15% rise in IOP after enrollment and one minute after intubation, the IOP increased to 36.57%. A substantial rise in beat frequency and circulatory pressure was renowned in Set S after operator acceptance in addition intubation associated to Set V. Conclusion: Propofol and vecuronium give a fantastic intubation illness and this is an appropriate operator for tracheal intubation in elective ophthalmic intervention and crisis where an IOP rise is unfortunate. Key words: Anesthesia, ANOVA, Intraocular pressure, ophthalmic surgery.

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