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FACTORS THAT AFFECTING THE PROGNOSIS IN CHILDREN WITH HEMOLYTIC UREMIC SYNDROME

Dr Shazia Munawar, Dr Naheed , Dr Jamil Ur Rahman

Objective: The aim of this study was to assess various factors that influence prognosis in children with hemolytic uremic syndrome (HUS). Place and Duration: In the Department of Pediatrics, Services Hospital Lahore for one year duration form March 2018 to March 2019 Methods: Forty children with a classic HUS clinical picture were selected. Boys and girls between the ages of two months and ten were equally affected. 35 patients (87.5%) had diarrhea in the past, which was bloody in 25. All were treated with peritoneal dialysis during the first 24 hours. Freshly frozen plasma (FFP) was transfused during the first two days in all but two patients who were transfused on the third to fifth day of admission. Results: Fifteen patients died (37.5%); of these, 12 (80%) had diarrhea for over 7 days, 11 (73%) had pronounced neutrophilia, and 9 (60%) had significant neurological symptoms. Eleven of fifteen patients were transfused with FFP after the third hospitalization clay. Statistical analysis of mortality data revealed the following prognostic factors in HUS in children: mortality is higher in people with a longer prodromal period (p

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