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TITLE:

TO DETERMINE STATUS EPILEPTICUS (SE) OUTCOMES AND RISK FACTORS ASSOCIATED WITH IT: A CROSS SECTIONAL STUDY

AUTHORS:

Dr. Naveeda Shoukat, Dr Rubia Nawabi, Dr. Mehvish Mandokhail

ABSTRACT:

Objective: The aim of this study is to assess the outcome of status epilepticus in patients admitted with seizure in hospital of Capital City of Pakistan. Study Design: Cross sectional study Place and Duration of Study: This study was conducted at Pakistan Institute of Medical Sciences, Islamabad from November, 2018 to October, 2019. Materials and Methods: 108 patients in number were included in the study after informed consent in written form. Patients included in the study who fulfilled the inclusion criteria. Data was collected in preform proforma in 108 cases following the selection criteria. Patients were recruited after informed consent of the patients and ethical approval from the institution. The patients were followed till discharge and all the information collected in preformed proforma. Standard protocol followed for the treatment of status epilepticus. Outcome measured in the form of fully recovered, recovered with neurological deficit & death. The data were analyzed on version 20. Descriptive statistics was used to summarize the categorical variables such as gender, history of epilepsy, status epileptic in past, drug withdrawal, febrile illness, mortality presented as frequencies and percentages while continuous variable like age was presented as Mean ± SD. Chi-square test p- value ≤ 0.05 was taken as significant. Results: Among 108 patients 60(56.6%) were male & 48(44.4%) were female, mean age of study group were 31.3±13.5 years. The results found that only 2 (1.9%) patients were expired (p < 0.01) while 106 patients fully recovered without any neurological deficit. Conclusion: We concluded after this study that early recognition & prompt treatment of the epileptic patients in status epilepticus have better outcome. Key Words: Status Epilepticus, Convulsive Status Epilepticus, outcome.

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