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PREDICTION OF ENDOMETRIAL CANCER WITH THE VOULME OF ENDOMETRIAL FLUID COLLECTION

Dr Hammad Farooq, Dr Muhammad Tabish Nisar, Dr Hafiz Muhammed Wasim Murtaza

Objective: The aim of this research work is to calculate the volume of endometrial fluid collection through ultrasonography for the prediction of the endometrial cancer among asymptomatic post-menopausal females. Methodology: In this research work, we analyzed 150 asymptomatic post-menopausal females retrospectively from April 2016 to March 2019. We included the patients with endometrial hyperplasia or neoplasia in Group-1, and patients with end metritis, insufficient tissue or endometrial atrophy in Group-2. We compared the patients of both groups with respect to primary and secondary outcomes. Primary outcomes were the correlations between thickness of endometrium and volume of endometrial fluid collection and secondary outcomes were the correlations between traits of demography and volume of endometrial fluid collection. Results: We were unable to found any association volume of endometrial fluid collection and thickness of single-layer endometrium (P = 0.360). Likewise, there was no correlation of demographic traits with the endometrial fluid collection (P > 0.050). However, both the volume of endometrial fluid collection and single-layer thickness of endometrium were thicker in the patients of Group-1 in comparison with the patients of Group-2 (4.80 ± 1.90 mm vs 3.70 ± 2.50 mm; and 5.70 ± 9.40 mm vs 2.70 ± 2.50 mm, respectively) (P values < 0.050). Conclusion: The findings of this work could not recommend the cutoff value for volume of endometrial fluid collection and endometrial thickness, this important to note that 2.0% is the clinically significant malignancy rate. Thus, It is important to assess the post-menopausal patients with endometrial fluid collection for the endometrial sampling. Keywords: Menopause, Ultrasonography, Thickness, Endometrium, Demography, Endometrial Fluid Collection.

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