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TITLE:

A RANDOMIZED CONTROLLED TRIAL TO KNOW THE OUTCOME OF OPEN VERSUS MINICHOLECYSTECTOMY FOR CHOLELITHIASIS

AUTHORS:

Dr. Misbah Mushtaq, Dr. Kiran Mushtaq, Dr. Shaista Batool

ABSTRACT:

Objective: To compare the outcome of mini cholecystectomy with open cholecystectomy in the treatment of cholelithiasis. Study Design: A randomized controlled trial. Place and Duration: The study was carried out in Surgical department of Nishtar Hospital Multan for One year duration from July 2018 to June 2019. Methods: A total of 100 cases; Fifty cases were included in each group. 100 patients who met the inclusion criteria entered the OPD were selected. Demographic data were recorded. All patients were diagnosed based on clinical history, clinical examination and related research. Consent was received in writing. Data were entered and analyzed using SPSS 18.0. Data were analyzed according to the proposed analysis plan. Results: The mean age of the patients was 39.96 ± 3.84 years. The age range of the patients was 30-48 years. Mean hospital stay in Group A was 5.38 ± 1.15 and mean hospital stay in Group B was 3.02 ± 0.58 days, respectively. At the first visit, 14 patients (28%) in Group B and only 1 patient (2%) in Group A had a wound infection. According to P value, wound infection was significantly associated with the treatment group. Patients in Group A had a lower infection rate than Group B patients. That is, (p = 0.000 value) At the second visit, 8 patients (16%) and 3 patients in Group B had a wound infection in Group A. At the second visit, wound infection was statistically identical in both treatment groups. that is, (p = 0.110 value). Only 44 patients (88%) had severe pain in Group B, and only 12 patients (24%) had severe pain in Group A. Considering this result, the rate of severe pain at 12 hours was higher in Group B patients than in Group A patients. Conclusion: Mini cholecystectomy is an effective procedure and associated with less postoperative pain and infection with less discomfort for patients and shorter hospital stay. Key words: Cholelithiasis, conventional, cholecystectomy, laparoscopic, mini-laparoscopic.

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