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CLINICOPATHOLOGICAL PATTERN OF GYNAECOLOGICAL MALIGNANCIES AT OBSTETRICS AND GYNAECOLOGICAL UNIT, AZIZ BHATTI SHAHEED TEACHING HOSPITAL GUJRAT

DR SADIQ JAN, Dr Uzma Mumtaz, Dr Rukhsana Perveen

Aim: To examine the clinical-pathological pattern of gynaecological malignancies, including incidence, clinical presentation, age distribution, histopathological types and stage at diagnosis. Study design: A descriptive observational study. Place and Duration: In the Obstetrics and Gynaecology unit, Aziz Bhatti Shaheed Teaching Hospital Gujrat for two year duration from February 2017 to February 2019. Methods: 10,799 total women were admitted during the study time. All patients with genital tumours were selected by purposive non probability sampling. Patients with benign tumours were not included. The physical examination, history and study details were collected. Necessary surgical procedures were performed. The tumours were graded clinically, surgically and confirmed histopathologically. Results: The gynaecological cancer incidence in our facilities was 35 (0.32%), in total 10 799. The most common ovarian cancer was 22 (62.86%), then 8 (22.86%) of uterus and 5 (14.29%) of cervix. In the 50-75 age group, ovarian cancer was noted usually, in the 60-75 age group uterine cancer, and cervical cancer in the 40-49 age group. The most common ovarian cancer was serous cystadenocarcinoma, 12 (54.55%); and squamous cell cancer3 (60%), endometrioid adenocarcinoma 6 (75%), were the most common types of cervical and uterine cancer. Gastrointestinal upset, 11 (31%), abdominal distension, 13 (37%), postmenopausal bleeding 11 (31%), vaginal discharge 11 (31%) and irregular vaginal bleeding 9 (26%) were the utmost usual symptoms. Most ovarian cancers were in advanced stage 21 (95.4%), and uterine cancers were diagnosed usually at initial stages 5 (62.5%). Conclusion: The most common gynaecological cancer is ovarian cancer in advanced stages. More thorough study of epidemiology and the screening methods should be carried out effectively to decrease the gynaecological cancer burden and awareness of early symptoms in women. Key words: Gynaecological malignancies, endometrium, staging, ovarian cancer.

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