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TITLE:

A STUDY TO ASSESS THE EFFECTS OF VITAMIN D IN PREVENTION FROM EARLY CHILDHOOD CARIES (ECC)

AUTHORS:

Dr Mariam Siddique, Ayesha Iqbal, Dr Noor-ul-Huda

ABSTRACT:

Objective: We conducted this study to assess the effects of vitamin D in prevention from Early Childhood Caries (ECC). Study Design: Cross sectional study. Place and Duration of study: The study was conducted at Jinnah Hospital, Lahore from August, 2018 to July, 2019. Material and Methods: Eighty children, between 2-8 years of age, were recruited after fulfilling a questionnaire from their parents or caregiver. The sample population was divided into two groups. Group 1 consisted of children suffering from dental caries and was comprised of 60 patients. Group 2 consisted of children with sound healthy teeth and was comprised of 20 children. Questions assessing children’s socioeconomic background, dietary habits particularly frequency of sweet and milk intake, outdoor activity and dental hygiene related behavior were included. The diagnosis of childhood caries was based on oral health diagnostic criteria defined by World Health Organization (WHO). Overall total caries score (decayed missing filled teeth index) was obtained. Levels of 25-hydroxy vitamin D (25(OH) D) was measured from serum samples of the children participating in this study using enzyme linked immunosorbent assay (ELISA). Correlation analysis was done with Pearson correlation and t-test was applied. Results: Results have established association of Vitamin D levels in children with early childhood caries. Pearson correlation and t-test have revealed that total decayed, missing, filled primary teeth (DMFT) caries score was also associated with 25(OH) D concentrations less than 30ng/ml, decreased oral hygiene, lower monthly income, increased sugar consumption, decreased milk intake and decrease outdoor activities. This cross-sectional study showed that carries and lower serum vitamin D are closely related with each other. Conclusion: Data from this cross-sectional study showed that dental caries and lower serum vitamin D were closely related. Improving children’s vitamin D status may be an additional preventive consideration to lower the risk for caries. Keywords: Early childhood caries (ECC), vitamin D, 25OHD (25 Hydroxy vitamin D), DMFT (Decayed Missed Filled Teeth).

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