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TITLE:

A CROSS-SECTIONAL STUDY TO DETERMINE THE PREVALENCE OF ANTI HCV VIRUS DURING PRENATAL PERIOD AND ITS CAUSAL RELATIONSHIP WITH RISK FACTORS

AUTHORS:

Momina Javaid, Ameerah khan, Saba Tariq Pervaiz Virk

ABSTRACT:

Objectives: To study the prevalence of Hepatitis C in pregnancy and its causal relationship, so that preventive measures can be taken, as Hepatitis C is like epidemic in Pakistan, Study Design: Cross-sectional study. Place and Duration: Department of Gynae/Obs Jinnah hospital, Lahore for the duration of one year starting from October, 2018 to September, 2019. Methodology: 1000 pregnant woman of 16-40 years presenting in Jinnah Hospital were enrolled for study. After informed consent their blood was obtained for anti HCV antibody analysis by a third generation Elisa technique. Sera testing positive were also confirmed by HCV RNA by PCR. Result: In our study out of 1000 pregnant woman 400 patients were HCV positive by Elisa method. Among these 400 patients 250 were confirmed of HCV RNA by PCR. 80% of patients were having previous surgery, 60% were multipara, 70% were low socio-economic class and 40% of patients were having history of previous blood transfusion. Conclusion: The prevalence of Hepatitis C is rapidly increasing in our population so proper health education and awareness should be improved and screening for HCV should be encouraged. Keywords: Hepatitis C Virus, Vertical Transmission, Prevalence.

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