ResearcherID - CLICK HERE Scientific Journal Impact Factor (SJIF-2020) - CLICK HERE

COMPARISON OF SAFETY AND EFFICACY OF INTRAVENOUS LABETALOL VERSUS HYDRALAZINE FOR MANAGEMENT OF HYPERTENSION IN PREGNANCY AT NISHTER HOSPITAL MULTAN

Muhammad Zulqarnain, Maimoona Shabbir, Muhammad Mubeen Yaseen

Background-In pregnancy to control the severe hypertension situation, there is no record about the safety of intravenous labetalol and hydralazine. Labetalol and hydralazine both have their own disadvantage and advantages. Methodology- In this method the comparison of the efficiency and safe reaction of labetalol and hydralazine was briefly examined in case of severe hypertension during pregnancy. 152 patients were selected and then these were subdivided into two groups. At start the blood pressure of all was noted then labetalol was given to one group and hydralazine was given to second group. After that the quantity of doses, side effect of both drug and the duration to meet the desired blood pressure was noted. Results- After first dose of hydralazine 69.5% patient were able to achieve the desired blood pressure that is comparatively lower than those patients who were given labetalol as 81.5% of them were able to achieve the desired blood pressure. It was find out in this research that with the help of labetalol patient could achieve the desired blood pressure faster that hydralazine. The side effects of both drugs were completely examined. Conclusion- Both drugs were proved very helpful in reducing the high blood pressure and getting the desired blood pressure conditions during pregnancy. It was also concluded in this study that labetalol is more efficient in reducing the blood pressure than the hydralazine. The side effects of hydralazine and labetalol is also comparable. Keywords: Labetalol, Hydralazine, Severe hypertension in pregnancy.

FULL TEXT