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PRESENT PRACTICE AND FUTURISTIC PERSPECTIVE ON THE MANAGEMENT OF HEPATITIS C VIRUS THROUGH SOFOSBUVIR

Dr. Junaid Hassan Khawaja, Dr. Sohail Raheem, Dr. Farooq Ashraf

Abstract: Our objective was to inspect the HCV Treatment with Sofosbuvir in Pakistan at Current Scenario and Future Perspective in Pakistan. It is endemic Hepatitis C Virus (HCV) with 5-8% predominance all in all populace. It is a worldwide issue with around 1.75 million new diseases yearly. There are a few HCV genotypes and antiviral treatments are genotype subordinate. In Pakistan genotype 3a is predominant trailed by demonstratively untypable HCV variations. With rough 70% chronicity rate around 399,000 individuals pass on every year from hepatitis C. As of late sofosbuvir is presented in Pakistan on vigorously markdown. In spite of the fact that sofosbuvir indicated generally excellent continued virological reaction (SVR) comprehensively however because of various ethnicity and hereditary cosmetics, it is critical to break down the medication viability in Pakistan. Beforehand interferon based antiviral regimens were the main decision for HCV treatment in Pakistan. The present information is exceptionally constrained and it is exceedingly needed investigations announcing the sofosbuvir treatment reaction from various ethnic gatherings from the entire nation. Accessible restricted information demonstrated that general SVR/fast virological reaction (RVR) is awesome. Keywords: Direct acting antiviral; Pakistan; HCV; Sofosbuvir; Treatment.

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