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THE USE OF MOUTHWASH WITH A HIGH ALCOHOL CONTENT (25%OR HIGHER) INCREASES THE RISK OF ORAL SQUAMOUS CELL CARCINOMA

Dr Wajiha Abbas, Dr Jahangir Hammad, Dr Umer Hussain

Abstract: Background: Recent studies have highlighted the role of alcohol as mouthwash antigens may lead to the higher oral cancer risk. Conclusively the reviews in literature are conflicting, especially the one showing enough evidences to accept the scheme that all mouthwash containing the alcohol contributed enough to elevate the oral cancer development. The current study aims to assess and associate the use of mouthwash with a high alcohol content in increasing the risk of oral squamous cell carcinoma. Methods: An observational case control design was used for the present study. A total of 100 cases and equal numbers of healthy controls were participated in the study. Candidates of age ≥18 years of either genders were included and divided in two groups i.e. cases with carcinoma and controls without carcinoma. And use of mouthwash with high alcohol concentration were noted. Odds ratio were calculated. Results: A total of 200 individuals participated in the current study. Out of the total participants 100 were case and 100 controls. In all individuals, cases are more likely to report the mouth wash use than the controls. 40% of the males and 60% of the females uses the mouthwash on regular basis. The crude odds ratio (OR) for using the mouthwash was 1.3 and 1.8 in males and females respectively. Conclusion: The current study concludes that regular use of mouthwash containing a high alcohol concentration lead to an increased oral cancer risk especially in females. Keywords: Mouthwash antigens, High alcoholic levels, Oral squamous cell carcinoma, Oral Cancer.

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