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TITLE:

RECURRENT URINARY TRACT INFECTION IN WOMEN

AUTHORS:

Dr Salman Hussain, Dr Nuzha Sajjad, Dr Sufyan Akram

ABSTRACT:

Abstract: Aim: To evaluate factors associated with recurrent urinary tract infection (UTI) in postmenopausal women. Method: a case-control study was conducted that comparing on 149 postmenopausal women who had a history of recurrent UTI (case patients) with 53 age-matched women without a history of UTI (control patients). Questionnaire was filled by each women providing demographic data, history and clinical characteristics of prior infections, and information regarding risk factors for UTI. In addition, each patient underwent a gynecologic evaluation, renal ultrasound and urine flow studies, and blood group and secretor status testing. Results and conclusion Three urologic factors—namely, incontinence (41% of case patients vs. 9.0% of control patients; ), presence of a cystocele (19% vs. 0%; P ! .001 P ! .001), and postvoiding residual urine (28% vs. 2.0%; )—were all strongly as- P = .00008 sociated with recurrent UTI. Multivariate analysis showed that urinary incontinence (odds ratio [OR], 5.79; 95% confidence interval [CI], 2.05–16.42; ), a history of UTI before P = .0009 menopause (OR, 4.85; 95% CI, 1.7–13.84; ), and nonsecretor status (OR, 2.9; 95% P = .003 CI, 1.28–6.25; ) were most strongly associated with recurrent UTI in postmenopausal P = .005 women.

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