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ANALYSIS OF BIOMARKERS IN CHRONIC PERIODONTITIS PATIENTS AMONG LOCAL POPULATION OF PAKISTAN

Dr. Eeshaa Ijaz, Dr. Muhammad Abdullah, Dr. Ambreen Naz

Abstract: Introduction: Chronic periodontitis, characterized by inflammation and destruction of periodontal supporting tissues, is one of the most common oral diseases worldwide. Aims and objectives: The main objective of the study is to analyse the biomarkers in chronic periodontitis patients among local population of Pakistan. Material and methods: This descriptive study was conducted in RHC Kot Qazi during November 2018 to March 2019. The data was collected with the permission of ethical committee of hospital. The data was collected from 100 patients. Five ml of fasting fresh blood sample was taken from all the patients. Results: The data was collected from 100 patients of both male and females. The mean age was 40.52±5.65 years. The mean values of serum ALP and Ca (10.28 mg/dL) was higher in female subjects as compared to the male subjects. The noted in females and positive in male subjects. Significant correlation of CPK (p = 0.001) was found with age in females while positive correlation was found for CPK in both the groups with other variables. Conclusion: It is concluded that chronic periodontitis was associated with systemic oxidative stress in human bodies. Female subjects are at greater risk of periodontitis and alveolar bone degradation in term of mean values of serum ALP and Ca than the male subjects.

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