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TITLE:

ANALYSIS OF LEVEL OF ANTIOXIDANTS AS A BIOMARKER OF CARDIOVASCULAR RISK IN OLDER POPULATION OF PAKISTAN

AUTHORS:

Dr Iqra Iftikhar, Dr Hiba Raza, Dr Hafiz Muhammad Fahad Nasarullah

ABSTRACT:

Abstract: Introduction: Cardiovascular disease (CVD) is the principal cause of death and disability in the developed countries and the most important cause of premature death worldwide, as outlined by the World Health Organization. Aims and objectives: The main objective of the study is to analyze the level of antioxidants as a biomarker of cardiovascular risk in older population of Pakistan. Material and methods: This cross sectional study was conducted in Allama Iqbal Memorial Teaching Hospital Sialkot During 2018. The data was collected from 100 patients of CVD. The data was collected for the analysis of blood antioxidants level among these patients. Blood sample was drawn for the analysis of serum antioxidants. Blood was centrifuged at 4000 rpm for the separation of serum. Then we find the serum antioxidants level by using Ohkawa et al., method. Results: The data was collected from 100 CVD patients. The mean age of the study patients was 54.4±10.6 years. Cigarette smoking was much more common in men than in women (32.6% vs. 0, p<0.001). The serum levels of creatinine, uric acid, and cTAS were significantly higher in men than in women (0.9±0.2 vs. 0.7±0.1, 7.6±2.1 vs. 6.8±2.3, and.0.4±0.0 vs. 0.3±0.1, respectively; p<0.001). Conclusion: It is concluded that age was not a determinant affecting the antioxidative barrier, regardless of the presence of CHD.

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