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ANALYSIS OF RISK OF INFECTIVE ENDOCARDITIS AFTER DENTAL PROCEDURE IN PAKISTAN

Dr Muhammad Alamgir, Dr Muhammad Imran Aslam, Dr Muhammad Younus Siddiqi

Abstract: Introduction: Infective endocarditis (IE) is an uncommon but potentially devastating disease, with an estimated annual incidence ranging from 2 to 7.9 per 100,000 individuals per year and a short-term mortality of 10% to 30%. Aims and objectives: The basic aim of the study is to analyse the risk of infective endocarditis after dental procedure in Pakistan. Material and methods: This descriptive study was conducted in Health department Punjab during December 2018 to April 2019. The data was collected from 100 patients. Five ml of fasting fresh blood sample was taken from all the patients. Then this blood was centrifuged at 4000 rpm for 10 minutes. Serum was separated and was analysed for the quantification of serum ALP, CPK and Ca using standard methods. Results: The data was collected from 100 patients of both male and females. The mean age was 40.52±5.65 years. The mean values of serum ALP (203.92 U/I) and Ca (10.28 mg/dL) was higher in female subjects as compared to the male subjects. The noted in females and positive in male subjects. Significant correlation of CPK (p = 0.001) was found with age in females while positive correlation was found for CPK in both the groups with other variables. Conclusion: It is concluded that the association between dental procedures and the risk of IE remained insignificant after adjustment for antibiotic use, indicating that dental procedures did not increase the risk of IE.

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