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TITLE:

ANALYSIS OF LOW SERUM FERRITIN LEVEL IN PATIENTS OF DECOMPENSATED CHRONIC LIVER DISEASE

AUTHORS:

Dr Hooria Shahzad, Dr Anoosh Fatima Gilani, Dr Haris Asif

ABSTRACT:

Abstract: Introduction: Liver fibrosis and its end-stage cirrhosis resulting from chronic liver injury are major causes of morbidity and mortality worldwide. Objectives of the study: To determine the frequency of low serum ferritin level in patients of decompensated chronic liver disease. Methodology of the study: This cross sectional study was conducted in Shalamar medical and dental college during November 2018 to March 2019. All adult and middle age 20-60 years patients of both genders, diagnosed case of chronic liver disease (previously or recently diagnosed having features of decompensated disease) were included in the study. The data was collected from 100 patients. History was taken in detail and thorough examination was performed. Results: The data was collected from 100 patients. Descriptive statistics of age (years) of patient was also calculated in terms of mean and standard deviation. Mean age (years) in the study was 53.74+8.66 with ranges from 20 to 60 years. Effect modifier like age was stratified and compared with frequency low serum ferritin level in patients of decompensated chronic live disease secondary to hepatitis C virus infection. Conclusion: It is concluded that elevated serum ferritin worsened liver injury. Hence it represents early marker for the severity of chronic liver disease, related both to the degree of liver fibrosis and to the necro-inflammatory activity.

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