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FABRICATION AND ASSESSMENT OF LEVOFLOXACIN CONTROLLED RELEASE MATRIX TABLETS

Thakur Sonia singh*,shalini, Pooja agarwal,savilna.D,Santhoshi M

Abstract: Vividly Oral drug delivery method is the most widely utilized routes for administration among all alternatives that have been explored for systemic delivery of drug via various pharmaceutical products of different dosage forms. Popularity of the route may be ease of administration as well as traditional belief that by oral administration the drug is due to the well absorbed into the food stuff ingested daily. The present work is aimed at preparing and evaluating Controlled-release (CR) matrix tablets of Levofloxacin using different polymers. From the results, formulationf6 containing Levofloxacin 250 mg, Xanthum gum evolved as the optimized formulation. The result revealing shows the feasibility of fabricating levofloxacin controlled release tablets significantly with better drug release profile. Keywords: Controlled release tablets, Levofloxacin, Fabrication & drug release.

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