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PREVALENCE OF HEPATITIS C IN PATIENTS WITH CHRONIC KIDNEY DISEASE AT A TERTIARY CARE HOSPITAL IN LAHORE

Dr.Muhammad Talha, Dr.Rabbia Imam, Dr.Muhammad Usman Shahid.

Abstract: Background: both hepatitis C and endless kidney infection (CKD) present an uncertain general medical issue. Hepatitis C infection (HCV) is effectively transmittable in hemodialysis units and kidney transplantation. HCV prompts an expansion in mortality and dreariness because of cirrhosis and hepatocellular carcinoma, while it quickens the movement of CKD. The target of the investigation was to depict the statistic, clinical/biochemical profile and commonness of patients with perpetual renal disappointment with HCV contamination. Techniques: This was a review examination of patients with endless renal disappointment who submitted to the tertiary consideration in Allama Iqbal Medical College Lahore from February 2016 to November 2018 at the Department of Medicine. Point by point clinical information was gathered alongside past reports lab and test. For HCV contamination they were performed in all patients. The determination of HCV was made by HCV RNA (RT PCR) and hostile to HCV positive IgG serology. Results: We included 67 patients with a mean age of 54 years (run 43-72 years) with a greater part of 76.1% of men and 71.6% in the age bunch 41-60 years. 31.4% were HCV positive, of which 81% were men. It was discovered that 7 patients had co-contamination with HIV and HBsAg. It was discovered that genotype 1 (72%) is more typical than genotype 3. Ultrasonography and endoscopy of the upper gastrointestinal tract indicated 57% individually with the pivot of the spleen expanded and the esophageal varices. Conclusion:the pervasiveness of HCV contamination in patients with incessant renal disappointment is high, with genotype 1 the most widely recognized. The HCV counter acting agent is negative, in this way recognition with HCV RNA is prescribed. Severe widespread precautionary measures must be utilized in emergency clinics and dialysis units to evade transmission. Key Words: Chronic kidney disease, Haemodialysis, Hepatitis C, Prevalence

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