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TITLE:

PARAPHENYLENEDIAMINE POISONING: SCIENTIFIC STRUCTURES, DIFFICULTIES IN ADDITION RESULT IN THE TERTIARY CARE INSTITUTION

AUTHORS:

Dr. Rafia Arshad, Dr. Fatima Bhatti, Dr Sajida Razzaq, Ammad Javaid Chaudhary.

ABSTRACT:

Abstract: Background: Paraphenylenediamine (PPD) is the material existing in hair colors that is absorbed in body cytochrome P455 organization, in addition is additional oxidized to the poisonous merchandise which might lead to numerous structure letdown. Objective: The objective of our existing research regulates occurrence of medical structures, difficulties in addition result in PPD intoxicated cases acknowledged to Intensive Care Unit of Services Hospital, Lahore Pakistan from May 2018 to December 2018. Methodology: Our current retrospective research remained led at ICU of Services Hospital, Lahore Pakistan from May 2018 to December 2018. The thorough medical past remained noted counting demographic outline, indications symbols also consequence. Judgement of PPD poisoning remained grounded on past of digestion also medical appearances. Results: Here stayed 1040 respondents of hair dye (PPD) poisoning. Here remained 360 (34.51%) men also 680 (65.49%) women (average age 23.09±9.43 years). Dysphagia remained detected in 1040, cervicofacial puffiness in 940 (91.52%), dyspnea in 929 (87.83%), widespread physique pain by muscle weakness in 714 (69.92%), reduced urine production in 190 (18.94%) also chocolate brown color urine in 778 (76.20%) respondents. Concerning cause of digestion of poison, suicidal purpose remained detected in 1023 (99.92%), accidental digestion in 9 (0.78%), homicidal in 2 (1.095%) also in 3 (1.993%) case’s purpose could not remain resolute. Altogether cases expended resident stone grounded hair dye through oral course. Forty cases stayed lost to follow up. Death degree in rest 996 cases stayed 15.6% (n=140) in man also 18.54% (n=174) in women. Conclusion: PPD poisoning remained extra known in women (67%) for suicidal resolve owing to calm obtainability, also remains related by the general death degree of 32.7%.

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