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RELATIONSHIP OF OBESITY AND OSTEOARTHRITIS

Dr Sayeda Rukhsana Noor, Dr Zaira Ashfaq, Dr Sadia Ghaffar.

Abstract: Osteoarthritis has been known as one out of ten most crippling diseases in the developed world and an important cause of pain and disability [1]. It is calculated that by the year 2040 78 million adults age 18 years will have been diagnosed with arthritis [2]. It is also the most common rheumatologic disorder in Asia [3]. Whereas in Pakistan, the prevalence of osteoarthritis is 28% in urban areas and 25% in rural areas. Study by Sun et al also suggested a possible role of elevated serum uric acid in the multifactorial etiology of generalized OA.15 However, the study by Bagge,16 and Hart17 found that serum uric acid levels do not vary at different categories of knee osteoarthritis. Out of 309 only 140 participants were recruited in this study in which the mean age was 52 years and the mean age of the onset of disease was 49 years. Females were 73% (n=102) while males were 27% (n=38). Categorization of age at disease onset revealed 39% (n=55) had the disease diagnosed when they were less than 45 years while remaining 61% (n=85) had the disease after 45 years. When duration of disease was categorized 89% (n=125) had osteoarthritis for less than 5 years while remaining 11% (n=15) had the disease for more than 5 years. Current study found that there is a positive relation between obesity and osteoarthritis.

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