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TITLE:

WBC COUNT, DURATION OF SYMPTOMS AND AGE IMPACT ON ACUTE APPENDICITIS AND SEVERITY OF DISEASE

AUTHORS:

Dr Muhammad Usama Javid, Dr Aneeqa Khalil, Dr. Farwa Yaqub

ABSTRACT:

Aim: To determine the relationship between the severity of acute appendicitis and the number of white blood cells, age and duration of symptoms. Study design: A cross-sectional study. Place and duration: In the Surgical department of District Headquarters Hospital Rawalpindi for one year duration from April 2019 to April 2020. Method: 242 patients with clinical and histological diagnosis of acute appendicitis were included in the study. Patients with simple acute appendicitis, purulent appendicitis, perforated appendicitis, or gangrenous appendicitis were included. Histological verification was performed on all samples. Results: Of the 242 patients, 174 are men and 68 women. The average age at the time of presentation for men was 22.68 ± 6.88, and for women 18.97 ± 5.37 days. The mean duration of symptoms was 1.98 ± 1.83 days in men and 1.52 ± 0.81 days in women. The mean duration of symptoms for simple acute appendicitis (group 1) was 1.92 ± 1.71, for purulent appendicitis (group 2) 1.38 ± 0.5, and for perforated appendicitis (group 3) 1.38 ± 0.69. The mean white blood cell counts for simple acute appendicitis, purulent appendicitis, and perforated appendicitis were 10,907.11 ± 3029,56, 10,300 ± 2401.38 and 12,461.11 ± 3643.22, respectively. No gangrenous appendicitis was observed. It was found that patients aged 25–35 have the highest number of WBC in various groups of severity of acute appendicitis (P = 0.004). No gangrenous appendicitis was observed. There was no significant relationship between the number of WBC and severity of results in appendicitis. There was a significant correlation between different age groups and the severity of the disease (P = 0.042). Conclusion: White blood cell counts and duration of symptoms are not good predictors of disease severity in appendicitis. In the adult population, an increase in age below 45 years increases the risk of appendicitis complications. KEYWORDS: attachments, complications

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