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TITLE:

EFFECT OF LAVANDULA OFFICINALIS HYDROALCOHOLIC EXTRACT ON BLOOD CELLS FACTORS IN MICE

AUTHORS:

Saeid Arefian and Mehrdad Modaresi *

ABSTRACT:

In this study, the effect of hydroalcoholic extract of lavender plant on the number of blood cells in small laboratory mice was investigated. Due to the medicinal use of lavender and some of its therapeutic effects, its effect on blood cell count is an important indicator in determining its positive and negative effects. In this study, 50 small female laboratory mice were divided into 5 control groups, placebo, 50 mg/kg dose, 100 mg/kg dose and 200 mg/kg dose and were treated with lavender extract for 20 days. After blood sampling and blood cell counting with an auto analyzer, a significant reduction in total white blood cell count was achieved in all three treatment groups, which was more significant with increasing dose. And in doses of 50 mg/kg and 100 mg/kg decreased the number of red blood cells. And hemoglobin levels of red blood cells and MCV and MCH indicators increased significantly. And the number of blood platelets was reduced at a dose of 200 mg/kg. Keywords: lavender, white blood cell, hydroalcoholic extract, small laboratory mice, red blood cell

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