::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

LEVELS OF ALT AND PLATELETS COUNT AMONG NON-WORKING PRIMIGRAVIDA GROUP WOMEN AS COMPARE TO WORKING PRIMIGRAVIDA WOMEN

AUTHORS:

Dr. Hadia Munir, Dr Umar Soban, Dr. Muhammad Zubair Fazal

ABSTRACT:

Introduction: Preeclampsia is one of the major health problems during pregnancy. It complicates 3%–8% of pregnancies and causes marked increase in perinatal, maternal morbidity, and mortality. Although the exact pathophysiology of preeclampsia is not completely understood, certain factors have been attributed to it, which include deficient trophoblastic invasion of the maternal vascular bed with subsequent reduction of placental blood flow. Aims and objectives: The basic aim of the study is to analyze the levels of ALT and platelets count among non-working Primigravida group women as compare to working Primigravida women comparatively. Methodology of the study: This was a randomized control study conducted in Shifa International hospital Islamabad during July 2019 to November 2019. We collected the data from 78 female patients who visits the OPD of a hospital. We divided the data into two groups one was those who were non-working Primigravida group women and second group was working Primigravida group. We collected all the basic characteristics of selected patients of both groups. We recorded their Hb levels, BMI and mean Alt levels for the analysis of liver function in pregnant women. Results: The data were collected from 78 patients with the mean age of sedentary life primigravida women are 26± 3.5 and regular exercising primigravida women are 27.4 ± 2.5. BMI of working women was noted as 26.4±2.4 and in non- working women as 24.12±2.1. Results shows that Hb level of working women becomes high as compared to non-working women. The mean level of ALT in non-exercising women are 45.6 ± 10.2 i.u/dl and in regular exercising women are 28.41 ± 7.4i.u/dl. Conclusion: It is concluded that working regular light exercise may reduce the chances of HELLP syndrome and pregnancy induced increased ALT.