::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

INVESTIGATION OF HEPATITIS B TRANSMISSION RISK FACTORS IN PATIENTS WITH HIV

AUTHORS:

Dr. Maleeha Saleem, Dr. Abdul Rafaih Khan, Dr. Nouman Ikram

ABSTRACT:

Aim: Co-infection with Hepatitis B (HBV) virus and HIV is common due to similarity of their transmission methods. However, the prevalence of concurrent infection in different societies, shows the crucial role of various risk factors in different populations. Therefore, the present study was performed to examine risk factors of transmission of HBV in patients with HIV. Methods: This case-control study was conducted on 60 HIV positive patients (in two 30-member experiment and control groups), who visited the Medicine departments of Holy Family Hospital Rawalpindi for one-year duration from March 2019 to March 2020. Registered patients were informed of the purpose and procedure of this study and were given written leave and excluded those who could not allow participation. All procedures in this study have been approved by the Ethical committee. They were adjusted in terms of age group (18-30, 30-40, 40-50, and 50-60), gender (male and female), and marital status (married, single, divorced, and widowed) and visited by an infectious disease’s specialist according to routine examinations. Data was recorded in a questionnaire for each subject. The mean age for the experimental group was 35±6.1, and for control group was 36.6± 5.7 years. Results and Conclusion: Both univariate and multivariate analyses of development of HBV infection and variables including Illegitimate sexual intercourse, use of intravenous injection drugs, positive history of imprisonment, and tattooing (p value < 0.05) showed existence of significant relationships. Injection of illegal intravenous drugs, history of imprisonment, illegitimate sexual intercourse, and tattooing are four important risk factors for transmission of HBV infection to HIV patients. In addition, the master risk reduction program may include provision of clean disposable tools for intravenous injection of drugs and tattooing. Keywords: Hepatitis B, HIV, Infection.