::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

PREVALENCE OF NON-HELICOBACTER PYLORI DUODENAL ULCER

AUTHORS:

Dr Saba Khurshid, Dr Aisha Khan, Dr Shazib Muhammad Saeed

ABSTRACT:

Introduction: Helicobacter species infect the gastrointestinal tracts of many animals from birds through humans. Some of these have been linked to a range of human diseases including chronic gastritis, peptic ulcer disease, mucosa-associated lymphoid tissue lymphoma, and gastric adenocarcinoma. Objectives: The main objective of the study is to analyse the prevalence of non-Helicobacter pylori duodenal ulcer. Material and methods: This descriptive study was conducted in Fatima Jinnah Medical University, Lahore during 2019. The data was collected from those patients who visited the OPD of the hospital. H pylori infection was confirmed by rapid urease test and histopathology, which was later used as the gold standard for the diagnosis. Results: Patients with NSAID-related duodenal ulcers had a higher male: female ratio of 4:1 with mean age of 62±16 years. Abdominal pain was common in H pylori infection 54% however, symptoms of abdominal pain, hematemesis and melena were relatively more in those with NSAID related duodenal ulcer covering 36%. H pylori and non-H pylori non-NSAID duodenal ulcer had a similar male:female ratio and mean age. Conclusion: It is concluded that H pylori infection-related duodenal ulcer is still common while NSAID-related duodenal ulcers occur in older age group.