::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

URINARY TRACT INFECTION AND ITS SENSITIVITY TO ANTIBIOTICS IN ACUTE CHILDHOOD DIARRHEA

AUTHORS:

Dr. Amina Pervaiz, Dr. Shezana Kosar, Dr. Sumaira Mushtaque

ABSTRACT:

Introduction: Diarrhea is the cause of nearly 18% of all child deaths. In early childhood, the symptoms of diarrhea can be similar to a urinary tract infection (UTI). The purpose of this study was to determine the incidence of UTIs and antibiotic susceptibility in children hospitalized with acute diarrhea. Place and Duration: In the Pediatric department of District Headquarter Hospital, Bagh for one-year duration from April 2019 to March 2020. Methods: All cases of acute diarrhea aged 1-60 months and hospitalized. They were included if diarrhea persisted 3 times a day and antibiotics had not been used in the last two days. The sensitivity and resistance of the cultures to common antibiotics was assessed. Results: Of all 575 patients, 31 (5.4%; 18 males ≈ 58%, 13 females ≈ 42%) had a UTI. There was no gender difference (p = 0.012), but 77.4% of the subjects were under 12 months of age (p = 0.012; OR = 2.89). The urine culture results were as follows: 27 cases (87.1%), Escherichia coli; two (6.5%), Enterococcus; one (3.2%), Pseudomonas; and one entity (3.2%), Klebsiella. Susceptibility to antibiotics was found to be 93.5% to nitrofurantoin and 61.3% to ceftriaxone and nalidixic acid. They were 67.7% resistant to co-trimoxazole and 64.5% to gentamicin. Conclusion: Although UTIs are not as common in acute childhood diarrhea, this should be taken into account especially in infancy. Key words: urinary tract infection (UTI), acute diarrhea, antibiotic sensitivity, antibiotic resistance, children