::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

PULMONARY FUNCTION TESTS IN PATIENTS WITH TYPE II DIABETES MELLITUS IN ASSOCIATION WITH FASTING BLOOD GLUCOSE

AUTHORS:

Dr. Sumaira Mushtaque, Dr. Shezana Kosar, Dr. Amina Pervaiz

ABSTRACT:

Background & Goals: Diabetes (DM) is an important public health issue worldwide associated with hormonal, metabolic and microvascular disorders. Angiopathic complications affect the eye, kidneys, nerves, cardiovascular and respiratory systems, which mainly depend on biochemical changes in the connective tissue. Place and Duration: In the Pulmonology and Department of Physiology, Sheikh Khalifa bin Zayed Al-Nayhan Combined Military Hospital, Rawalakot for one-year duration from February 2019 to February 2020. Material and Methods: This study includes 100 people aged 30 to 55 years, 50 diabetics (25 men and 25 women) and 50 (25 men and 25 women) healthy individuals. The pulmonary function tests were performed by the computerized spirometer in the Pulmonology and Department of Physiology. Results: The results of our study showed a statistically significant reduction in FEF50%, FEF75% & FEV1 /FVC ratio in diabetic male subjects when compared with control male subjects (p< 0.0001) and diabetic female subjects showed a reduction in FEV1/FVC which is not statistically significant (p = 0.0004) but we observed a statistically significant reduction in FEF50% & FEF75% in diabetic female subjects when compared with control female subjects (p< 0.0001). On spirometry, Diabetic subjects showed a significant reduction in FEV1/ FVC ratio, FEF 50%, FEF 75% relative to non-diabetic controls. Conclusion: From our study, we conclude that people with diabetes showed impaired lung function. We found a decline in FEV1 / FVC, FEF50% and FEF75% in diabetic patients compared to the control group. Keywords: Diabetes, Forced Vital capacity, forced expiratory Volume, Forced Expiratory Flow.