- CODEN : IAJPBB
- issn 2349-7750
TITLE:
A RETROSPECTIVE STUDY ON THE THYROID DYSFUNCTION IN PATIENTS WITH TYPE 2 DIABETES MELLITUS AND THE EFFECT OF DURATION OF DIABETES AND ANTI-GLYCEMIC MEDICATIONS ON MEAN HBA1C AND TSH LEVELS
AUTHORS:
Dr. Zahoor Ahmed Khan, Dr. Nasrullah Zadran, Dr. Muhammad Mashood
ABSTRACT:
Background: The relationship between type 2 diabetes and thyroid disorders is well established and requires testing a diabetic patient for the presence of thyroid abnormalities. Aim: to check the presence of hypothyroidism or hyperthyroidism in a sample of patients with type 2 diabetes and to check if anti-glycemic drugs have any effect on average levels of TSH and A1c. Methods: This is a retrospective study of the documentation of 1,341 patients with type 2 diabetes at the Endocrinology and Diabetology department of Services Hospital Lahore for one-year duration from March 2019 to March 2020. The data was taken from patient registration software and analyzed for the presence of hypothyroidism or hyperthyroidism. Results: Out of 1,341 patients with type 2 diabetes, 108 had thyroid dysfunction (8%), 7% had hypothyroidism, and 1% had hyperthyroidism. Mean TSH levels were significantly lower with diabetes duration> 5 years in patients with hypothyroidism (p = 0.032) and lower when metformin was introduced to treat hypothyroidism (p = 0.036). In patients with hyperthyroidism, this effect did not occur. Conclusion: Thyroid disorders in patients with type 2 diabetes are underestimated in our country, mean TSH levels are lower in patients with hypothyroidism when metformin was used, and lower in patients with diabetes lasting more than 5 years. Keywords: Type 2 diabetes, Hypothyroidism, Hyperthyroidism, Metformin.
FULL TEXT
Approved Journal
NLM ID:101711216 [Serial]
Included in EuroPub database
ICV 2015 - 61.16
Indexed In
S.J Impact Factor:7.157
cosmos Impact Factor:4.153
ICMJE Recommendations
IP Indexing Impact Factor: 2.76
Cover Page
