::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

ANTIDIABETIC ACTIVITY OF SULFONYLUREAS- A REVIEW

AUTHORS:

Nishad V M, Dr Prasobh G R, Mrs Sheeja Rekha A G, Visal C S

ABSTRACT:

Diabetes Mellitus is a chronic disease represented with high glucose blood levels. Although sulfonylurea compounds are the second preferred drug to treat Type II Diabetes (TYIID), they are still the most used agents due to their lower cost and as a mono-dosing. They are often prescribed for diabetic patients who are not of overweight or those for whom metformin is contraindicated or is not enough to achieve adequate glycemia control. They function by increasing insulin secretion from pancreatic beta cells. In the present study we will review various class of sulfonyl ureas. Key words- sulfonylureas, chemistry, Structural activity relationship