Dr Qurat-ul-ain, Dr Adeel Ahmad, Dr Ujala Khalid,
The clinical sign and symptoms of SIBO are loss of appetite, abdominal pain, nausea, bloating, and an uncomfortable feeling of fullness after eating, diarrhea, Unintentional weight loss and malnutrition. The common causes of SIBO are decreased intestinal mobility or any chronic disease such as diabetes. Irritable bowel syndrome, functional abdominal pain, and functional constipation are also found in functional gastrointestinal disorders. Poverty and nutrient malabsorption are associated with SIBO as a part of environmental enteropathy. In underdeveloped countries, when interpreting the concentrations of hydrogen (H2) and methane (CH4) in the lactulose breath test height impairment has seen in children with SIBO. While using H2 in other studies to interpret the test the conclusion was contrary, it does not show any association of height deficit in children with asymptomatic SIBO. It could be the justification for SIBO treatment regardless of symptoms. Total 140 patients age ranges from six months to 19 years were enrolled into the study. The statistical study did not show higher positivity, with a statistically significant difference in SIBO in any of the diseases that motivated the request for the H2 breath test. The current study has concluded that the production of H2 and CH4 increased in children during the colonic period of the breath test. And the patients with SIBO associated with gastrointestinal tract diseases have lower height values and those under ten years also have lower weight values when compared to patients without SIBO.